The aim of this text is to provide new insight into the role of oxidative stress in the progression of chronic renal disease and the pathogenesis of the co-morbidities associated with dialysis. Oxidative stress may be caused by chronic haemodialysis: the use of a bioincompatible dialysis system results in a dramatic increase in the production of reactive oxygen species, thus reducing antioxidant defence mechanisms. Possible solutions to this problem are discussed: there is both clinical and experimental evidence that oxidant stress can be prevented, or at least reduced, by usin
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